The MEGA Mouse Universal Genotyping Array (MUGA) provides 76,000 SNP markers built on the Illumina Infinium platform. The SNP markers are distributed throughout the mouse genome. The SNPs were selected to be maximally informative and independent—making the array a highly cost effective tool for many genotyping applications by maximizing information per marker.
The MEGA MUGA design criteria make it optimal for detecting heterozygous regions and discriminating between haplotypes in homozygous regions. The array’s allele frequencies and haplotypes were derived from the eight laboratory mouse strains that are founders of the Collaborative Cross.